PCGF2 monoclonal antibody (M05), clone 2D6
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More Files
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Western Blot (Tissue lysate)
PCGF2 monoclonal antibody (M05), clone 2D6. Western Blot analysis of PCGF2 expression in human placenta.
Western Blot detection against Immunogen (32.23 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PCGF2.
Immunogen
PCGF2 (AAH04858.1, 236 a.a. ~ 294 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LTLATVPTPSEGTNTSGASECESVSDKAPSPATLPATSSSLPSPATPSHGSPSSHGPPA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (32.23 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PCGF2 monoclonal antibody (M05), clone 2D6. Western Blot analysis of PCGF2 expression in human placenta.Western Blot (Recombinant protein)
ELISA
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Gene Info — PCGF2
Entrez GeneID
7703GeneBank Accession#
BC004858Protein Accession#
AAH04858.1Gene Name
PCGF2
Gene Alias
MEL-18, MGC10545, RNF110, ZNF144
Gene Description
polycomb group ring finger 2
Omim ID
600346Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses. [provided by RefSeq
Other Designations
ring finger protein 110|zinc finger protein 144
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Interactome
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Disease
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