ZNF9 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ZNF9 full-length ORF ( AAH00288, 1 a.a. - 170 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44.44
Interspecies Antigen Sequence
Mouse (100); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CNBP
Entrez GeneID
7555GeneBank Accession#
BC000288Protein Accession#
AAH00288Gene Name
CNBP
Gene Alias
CNBP1, DM2, FLJ11631, PROMM, RNF163, ZCCHC22, ZNF9
Gene Description
CCHC-type zinc finger, nucleic acid binding protein
Gene Ontology
HyperlinkGene Summary
This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
cellular nucleic acid binding protein|erythroid differentiation-related|myotonic dystrophy type 2 protein|sterol regulatory element-binding protein|zinc finger protein 273|zinc finger protein 9|zinc finger protein 9 (a cellular retroviral nucleic acid bin
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Interactome
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Disease
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Publication Reference
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Mutant (CCTG)n Expansion Causes Abnormal Expression of Zinc Finger Protein 9 in Myotonic Dystrophy Type 2.
Raheem O, Olufemi SE, Bachinski LL, Vihola A, Sirito M, Holmlund-Hampf J, Haapasalo H, Li YP, Udd B, Krahe R.
The American Journal of Pathology 2010 Dec; 177(6):3025.
Application:WB-Ti, Human, Human muscle samples.
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Mutant (CCTG)n Expansion Causes Abnormal Expression of Zinc Finger Protein 9 in Myotonic Dystrophy Type 2.
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