ZIC2 monoclonal antibody (M02), clone 3G5
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More Files
- More Functions
Western Blot detection against Immunogen (33.26 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant ZIC2.
Immunogen
ZIC2 (NP_009060, 151 a.a. ~ 216 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SDAQGHLLFP GLPEQHGPHG SQNVLNGQMR LGLPGEVFGR SEQYRQ VASP RTDPY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.26 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ZIC2
Entrez GeneID
7546GeneBank Accession#
NM_007129Protein Accession#
NP_009060Gene Name
ZIC2
Gene Alias
HPE5
Gene Description
Zic family member 2 (odd-paired homolog, Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq
Other Designations
OTTHUMP00000018633|Zic family member 2 (odd-paired Drosophila homolog)|Zinc finger protein of the cerebellum 2|zinc finger protein of the cerebellum 2
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Interactome
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Pathway
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Disease
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