ZIC1 monoclonal antibody (M03), clone 4D11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ZIC1.
Immunogen
ZIC1 (NP_003403, 2 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LLDAGPQYPAIGVTTFGASRHHSAGDVAERDVGLGINPFADGMGAFKLNPSSHELASAGQTAFTSQAPGYAAAAALGHHHHPGHVGSYSSAAFN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.08 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ZIC1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — ZIC1
Entrez GeneID
7545GeneBank Accession#
NM_003412Protein Accession#
NP_003403Gene Name
ZIC1
Gene Alias
ZIC, ZNF201
Gene Description
Zic family member 1 (odd-paired homolog, Drosophila)
Omim ID
600470Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq
Other Designations
Zic family member 1 (odd-paired Drosophila homolog)|Zinc finger protein of the cerebellum 1|zinc finger protein of the cerebellum 1
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Interactome
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Disease
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