YWHAH monoclonal antibody (M04), clone 6A12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant YWHAH.
Immunogen
YWHAH (AAH03047, 71 a.a. ~ 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged YWHAH is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — YWHAH
Entrez GeneID
7533GeneBank Accession#
BC003047Protein Accession#
AAH03047Gene Name
YWHAH
Gene Alias
YWHA1
Gene Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Omim ID
113508Gene Ontology
HyperlinkGene Summary
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq
Other Designations
14-3-3 eta
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Interactome
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Pathway
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Disease
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