XRCC4 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
XRCC4 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC4 expression in mouse liver.
Western Blot (Transfected lysate)
Western Blot analysis of XRCC4 expression in transfected 293T cell line (H00007518-T02) by XRCC4 MaxPab polyclonal antibody.
Lane 1: XRCC4 transfected lysate(38.3 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC4 transfected lysate using anti-XRCC4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC4 MaxPab mouse polyclonal antibody (B01) (H00007518-B01).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human XRCC4 protein.
Immunogen
XRCC4 (NP_071801.1, 1 a.a. ~ 336 a.a) full-length human protein.
Sequence
MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMAMEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPAEVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRFILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQTDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSRPDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (74); Rat (70)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
XRCC4 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC4 expression in mouse liver.Western Blot (Transfected lysate)
Western Blot analysis of XRCC4 expression in transfected 293T cell line (H00007518-T02) by XRCC4 MaxPab polyclonal antibody.
Lane 1: XRCC4 transfected lysate(38.3 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC4 transfected lysate using anti-XRCC4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC4 MaxPab mouse polyclonal antibody (B01) (H00007518-B01). -
Gene Info — XRCC4
Entrez GeneID
7518GeneBank Accession#
NM_022406.1Protein Accession#
NP_071801.1Gene Name
XRCC4
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 4
Omim ID
194363Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq
Other Designations
DNA repair protein XRCC4|X-ray repair cross complementing protein 4|X-ray repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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