XRCC3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-XRCC3 full-length
Host
Human
Theoretical MW (kDa)
37.8
Interspecies Antigen Sequence
Mouse (73); Rat (73)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-XRCC3 antibody (H00007517-D01P) by Western Blots.
SDS-PAGE Gel
XRCC3 transfected lysate.
Western Blot
Lane 1: XRCC3 transfected lysate ( 37.80 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — XRCC3
Entrez GeneID
7517GeneBank Accession#
NM_005432.2Protein Accession#
NP_005423.1Gene Name
XRCC3
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 3
Omim ID
600675Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
DNA repair protein XRCC3|RAD51-like|X-ray repair cross complementing protein 3|X-ray-repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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