XRCC3 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
XRCC3 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC3 expression in human liver.
Western Blot (Cell lysate)
XRCC3 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC3 expression in K-562.
Western Blot (Transfected lysate)
Western Blot analysis of XRCC3 expression in transfected 293T cell line (H00007517-T02) by XRCC3 MaxPab polyclonal antibody.
Lane 1: XRCC3 transfected lysate(37.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC3 transfected lysate using anti-XRCC3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC3 MaxPab mouse polyclonal antibody (B01) (H00007517-B01).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human XRCC3 protein.
Immunogen
XRCC3 (NP_005423.1, 1 a.a. ~ 346 a.a) full-length human protein.
Sequence
MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
XRCC3 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC3 expression in human liver.Western Blot (Cell lysate)
XRCC3 MaxPab rabbit polyclonal antibody. Western Blot analysis of XRCC3 expression in K-562.Western Blot (Transfected lysate)
Western Blot analysis of XRCC3 expression in transfected 293T cell line (H00007517-T02) by XRCC3 MaxPab polyclonal antibody.
Lane 1: XRCC3 transfected lysate(37.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of XRCC3 transfected lysate using anti-XRCC3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with XRCC3 MaxPab mouse polyclonal antibody (B01) (H00007517-B01). -
Gene Info — XRCC3
Entrez GeneID
7517GeneBank Accession#
NM_005432.2Protein Accession#
NP_005423.1Gene Name
XRCC3
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 3
Omim ID
600675Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
DNA repair protein XRCC3|RAD51-like|X-ray repair cross complementing protein 3|X-ray-repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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