XRCC2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human XRCC2 full-length ORF ( AAH42137, 1 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
56.54
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — XRCC2
Entrez GeneID
7516GeneBank Accession#
BC042137Protein Accession#
AAH42137Gene Name
XRCC2
Gene Alias
DKFZp781P0919
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 2
Omim ID
600375Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq
Other Designations
DNA repair protein XRCC2|RAD51-like|X-ray repair cross complementing protein 2|X-ray repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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