XRCC2 monoclonal antibody (M01), clone 2H4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of XRCC2 expression in transfected 293T cell line by XRCC2 monoclonal antibody (M01), clone 2H4.
Lane 1: XRCC2 transfected lysate(32 KDa).
Lane 2: Non-transfected lysate.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged XRCC2 is approximately 0.3ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to XRCC2 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (56.54 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant XRCC2.
Immunogen
XRCC2 (AAH42137, 1 a.a. ~ 280 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MCSAFHRAESGTELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSSEEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQKASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSNQFSLVSRCLKSNSLKKHFFIIGESGVEFC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (56.54 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of XRCC2 expression in transfected 293T cell line by XRCC2 monoclonal antibody (M01), clone 2H4.
Lane 1: XRCC2 transfected lysate(32 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged XRCC2 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to XRCC2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — XRCC2
Entrez GeneID
7516GeneBank Accession#
BC042137Protein Accession#
AAH42137Gene Name
XRCC2
Gene Alias
DKFZp781P0919
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 2
Omim ID
600375Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq
Other Designations
DNA repair protein XRCC2|RAD51-like|X-ray repair cross complementing protein 2|X-ray repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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Publication Reference
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Dysfunctional homologous recombination mediates genomic instability and progression in myeloma.
Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC.
Blood 2008 Dec; 113(10):2290.
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Dysfunctional homologous recombination mediates genomic instability and progression in myeloma.
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