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XRCC1 Pre-design Chimera RNAi

  • Catalog # : H00007515-R01
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  • Specification
  • Product Description:
  • Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 1 (XRCC1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006297
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7515
  • Gene Name:
  • XRCC1
  • Gene Alias:
  • RCC
  • Gene Description:
  • X-ray repair complementing defective repair in Chinese hamster cells 1
  • Gene Summary:
  • The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq
  • Other Designations:
  • DNA repair protein XRCC1,X-ray repair cross complementing protein 1,X-ray-repair, complementing defective, repair in Chinese hamster
  • Gene Pathway
  • Related Disease
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