XPNPEP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human XPNPEP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human XPNPEP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human XPNPEP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — XPNPEP1
Entrez GeneID
7511GeneBank Accession#
XPNPEP1Gene Name
XPNPEP1
Gene Alias
SAMP, XPNPEP, XPNPEPL, XPNPEPL1
Gene Description
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
Omim ID
602443Gene Ontology
HyperlinkGene Summary
X-prolyl aminopeptidase (EC 3.4.11.9) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-prolyl aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby complementing the pancreatic peptidases. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine (Blau et al., 1988 [PubMed 3141711]).[supplied by OMIM
Other Designations
OTTHUMP00000020457|OTTHUMP00000058856|X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (SAMP, XPNPEP, XPNPEPL)|X-prolyl aminopeptidase (aminopeptidase P)-like
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Interactome
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Disease
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