Immunoprecipitation of XPA transfected lysate using anti-XPA MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with XPA purified MaxPab mouse polyclonal antibody (B01P) (H00007507-B01P).
This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq