WNT9A (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human WNT9A full-length ORF ( NP_003386, 1 a.a. - 365 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLDGSPLARWLAAAFGLTLLLAALRPSAAYFGLTGSEPLTILPLTLEPEAAAQAHYKACDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFKETAFLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREAWQWGGCGDNLKYSSKFVKEFLGRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKHKYETALKVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPELVHLDDSPSFCLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRWCCYVECRQCTQREEVYTCKG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
65.78
Interspecies Antigen Sequence
Mouse (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — WNT9A
Entrez GeneID
7483GeneBank Accession#
NM_003395.1Protein Accession#
NP_003386Gene Name
WNT9A
Gene Alias
MGC138165, MGC141991, WNT14
Gene Description
wingless-type MMTV integration site family, member 9A
Omim ID
602863Gene Ontology
HyperlinkGene Summary
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. [provided by RefSeq
Other Designations
wingless-type MMTV integration site family, member 14
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Interactome
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Pathway
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Disease
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Publication Reference
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Dysregulation of the Wnt signaling pathway and synovial stem cell dysfunction in osteoarthritis development.
Huang J, Chen C, Liang C, Luo P, Xia G, Zhang L, Wang X, Wen Z, Cao X, Wu S.
Stem Cells and Development 2020 Apr; 29(7):401.
Application：Func, Human, Human synovial mesenchymal stem cells.
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Identification of fibronectin as a major factor in human serum to recruit subchondral mesenchymal progenitor cells.
Kulawig R, Kruger JP, Klein O, Konthur Z, Schutte H, Klose J, Kaps C, Endres M.
The International Journal of Biochemistry & Cell Biology 2013 Jul; 45(7):1410.
Application：Func, Human, Human mesenchymal progenitor cells.
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Dysregulation of the Wnt signaling pathway and synovial stem cell dysfunction in osteoarthritis development.
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