VWF monoclonal antibody (M02), clone 1A11
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More Files
- More Functions
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Specification
Product Description
Mouse monoclonal antibody raised against partial propeptide of human VWF protein.
Immunogen
VWF (AAH22258.1, 1 a.a. ~ 273 a.a) full-length human protein.
Sequence
MGAQDEEEGIQDLDGLLVFDKIVEVTLLNLPWYNEETEGQRGEMTAPKSPRAKIRGTLCAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSSCNISSGEMQKVGVDWPGCTWMVCDFWI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (55.77 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of VWF expression in transfected 293T cell line by VWF monoclonal antibody (M02), clone 1A11.
Lane 1: VWF transfected lysate(30.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged VWF is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — VWF
Entrez GeneID
7450GeneBank Accession#
BC022258.1Protein Accession#
AAH22258.1Gene Name
VWF
Gene Alias
F8VWF, VWD
Gene Description
von Willebrand factor
Omim ID
193400Gene Ontology
HyperlinkGene Summary
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq
Other Designations
coagulation factor VIII VWF
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Interactome
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Pathway
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Disease
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