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VMD2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007439-T01
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-VMD2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 66.55
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-VMD2 antibody (H00007439-B01) by Western Blots.
    Western Blot
    QC Testing of H00007439-T01
    Lane 1: BEST1 transfected lysate ( 69.1 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00007439-T01
    BEST1 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7439
  • Protein Accession#:
  • -
  • Gene Name:
  • BEST1
  • Gene Alias:
  • ARB,BEST,BMD,TU15B,VMD2
  • Gene Description:
  • bestrophin 1
  • Gene Summary:
  • This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms
  • Other Designations:
  • Best disease,vitelliform macular dystrophy protein 2
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