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VMD2 Pre-design Chimera RNAi

  • Catalog # : H00007439-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens vitelliform macular dystrophy 2 (Best disease, bestrophin) (VMD2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_004183
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7439
  • Gene Name:
  • BEST1
  • Gene Alias:
  • ARB,BEST,BMD,TU15B,VMD2
  • Gene Description:
  • bestrophin 1
  • Gene Summary:
  • This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms
  • Other Designations:
  • Best disease,vitelliform macular dystrophy protein 2
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