Immunoprecipitation of EZR transfected lysate using anti-EZR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EZR purified MaxPab mouse polyclonal antibody (B01P) (H00007430-B01P).
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq