VEGFC (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human VEGFC partial ORF ( NP_005420, 112 a.a. - 227 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AHYNTEILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.5
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — VEGFC
Entrez GeneID
7424GeneBank Accession#
NM_005429Protein Accession#
NP_005420Gene Name
VEGFC
Gene Alias
Flt4-L, VRP
Gene Description
vascular endothelial growth factor C
Omim ID
601528Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D. [provided by RefSeq
Other Designations
FLT4 ligand DHM|vascular endothelial growth factor-related protein
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Interactome
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Pathway
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Disease
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