UVRAG 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
UVRAG transfected lysate.
Western Blot
Lane 1: UVRAG transfected lysate ( 78.2 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-UVRAG full-length
Host
Human
Theoretical MW (kDa)
78.2
Interspecies Antigen Sequence
Mouse (88); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-UVRAG antibody (H00007405-B01) by Western Blots.
SDS-PAGE Gel
UVRAG transfected lysate.
Western Blot
Lane 1: UVRAG transfected lysate ( 78.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — UVRAG
Entrez GeneID
7405GeneBank Accession#
BC064837Protein Accession#
AAH64837Gene Name
UVRAG
Gene Alias
DHTX, p63
Gene Description
UV radiation resistance associated gene
Omim ID
602493Gene Ontology
HyperlinkGene Summary
This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq
Other Designations
UV radiation resistance associated|disrupted in heterotaxy
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Interactome
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Disease
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