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Last updated: 2017/10/22

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UTRN Pre-design Chimera RNAi

  • Catalog # : H00007402-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens utrophin (homologous to dystrophin) (UTRN), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_007124
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7402
  • Gene Name:
  • UTRN
  • Gene Alias:
  • DMDL,DRP,DRP1,FLJ23678
  • Gene Description:
  • utrophin
  • Gene Summary:
  • This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017350,OTTHUMP00000040139,dystrophin-related protein
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