USP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human USP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human USP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human USP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — USP1
Entrez GeneID
7398GeneBank Accession#
USP1Gene Name
USP1
Gene Alias
UBP
Gene Description
ubiquitin specific peptidase 1
Omim ID
603478Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
OTTHUMP00000010530|deubiquitinating enzyme 1|ubiquitin carboxyl terminal hydrolase 1|ubiquitin specific processing protease 1|ubiquitin specific protease 1|ubiquitin thiolesterase 1
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Interactome
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