UROS monoclonal antibody (M01), clone 1E11-B11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant UROS.
Immunogen
UROS (AAH02573, 1 a.a. ~ 265 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (54.89 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
UROS monoclonal antibody (M01), clone 1E11-B11 Western Blot analysis of UROS expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UROS is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — UROS
Entrez GeneID
7390GeneBank Accession#
BC002573Protein Accession#
AAH02573Gene Name
UROS
Gene Alias
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Gene Description
uroporphyrinogen III synthase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunther's disease). [provided by RefSeq
Other Designations
OTTHUMP00000020709|OTTHUMP00000020710|congenital erythropoietic porphyria
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Interactome
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Pathway
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