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NR1H2 rabbit monoclonal antibody

  • Catalog # : H00007376-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NR1H2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NR1H2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NR1H2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7376
  • GeneBank Accession#:
  • NR1H2
  • Gene Name:
  • NR1H2
  • Gene Alias:
  • LXR-b,LXRB,NER,NER-I,RIP15,UNR
  • Gene Description:
  • nuclear receptor subfamily 1, group H, member 2
  • Gene Summary:
  • The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM
  • Other Designations:
  • LX receptor beta,liver X receptor beta,liver X receptor-beta,nuclear orphan receptor LXR-beta,oxysterols receptor LXR-beta,steroid hormone-nuclear receptor NER,ubiquitously-expressed nuclear receptor
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