UGT8 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human UGT8 partial ORF ( NP_003351, 31 a.a. - 140 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FESHMYIFKTLASALHERGHHTVFLLSEGRDIAPSNHYSLQRYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVGNHALIQGLKKEKFDLLLVDPN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UGT8
Entrez GeneID
7368GeneBank Accession#
NM_003360Protein Accession#
NP_003351Gene Name
UGT8
Gene Alias
CGT
Gene Description
UDP glycosyltransferase 8
Omim ID
601291Gene Ontology
HyperlinkGene Summary
Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM
Other Designations
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)|UDP-galactose ceramide galactosyltransferase
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Interactome
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