UGT2B7 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human UGT2B7 protein.
Immunogen
UGT2B7 (ABM86740.1, 1 a.a. ~ 529 a.a) full-length human protein.
Sequence
MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSGENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67); Rat (68)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
UGT2B7 MaxPab polyclonal antibody. Western Blot analysis of UGT2B7 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of UGT2B7 expression in transfected 293T cell line (H00007364-T01) by UGT2B7 MaxPab polyclonal antibody.
Lane 1: UGT2B7 transfected lysate(58.19 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — UGT2B7
Entrez GeneID
7364GeneBank Accession#
DQ895814.2Protein Accession#
ABM86740.1Gene Name
UGT2B7
Gene Alias
UGT2B9
Gene Description
UDP glucuronosyltransferase 2 family, polypeptide B7
Omim ID
600068Gene Ontology
HyperlinkGene Summary
The UGTs (EC 2.4.1.17) serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.[supplied by OMIM
Other Designations
UDP glycosyltransferase 2 family, polypeptide B7|UDP-glucuronosyltransferase 2B7|UDP-glucuronyltransferase, family 2, beta-7
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Interactome
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Pathway
- Androgen and estrogen metabolism
- Ascorbate and aldarate metabolism
- Drug metabolism - cytochrome P450
- Drug metabolism - other enzymes
- Metabolic pathways
- Metabolism of xenobiotics by cytochrome P450
- Pentose and glucuronate interconversions
- Porphyrin and chlorophyll metabolism
- Retinol metabolism
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Disease
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