UGDH 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-UGDH full-length
Host
Human
Theoretical MW (kDa)
54.45
Interspecies Antigen Sequence
Mouse (98)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-UGDH antibody (H00007358-B01) by Western Blots.
SDS-PAGE Gel
UGDH transfected lysate.
Western Blot
Lane 1: UGDH transfected lysate ( 54.45 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — UGDH
Entrez GeneID
7358GeneBank Accession#
NM_003359.2Protein Accession#
NP_003350.1Gene Name
UGDH
Gene Alias
GDH, UDP-GlcDH, UDPGDH, UGD
Gene Description
UDP-glucose dehydrogenase
Omim ID
603370Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq
Other Designations
UDP-glucose 6-dehydrogenase|uridine diphospho-glucose dehydrogenase
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