UGDH monoclonal antibody (M01A), clone 1B7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant UGDH.
Immunogen
UGDH (NP_003350, 395 a.a. ~ 494 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIPKFSLQDPPNKKPKV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of UGDH expression in transfected 293T cell line by UGDH monoclonal antibody (M01A), clone 1B7.
Lane 1: UGDH transfected lysate (Predicted MW: 55 KDa).
Lane 2: Non-transfected lysate.
ELISA
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Gene Info — UGDH
Entrez GeneID
7358GeneBank Accession#
NM_003359Protein Accession#
NP_003350Gene Name
UGDH
Gene Alias
GDH, UDP-GlcDH, UDPGDH, UGD
Gene Description
UDP-glucose dehydrogenase
Omim ID
603370Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq
Other Designations
UDP-glucose 6-dehydrogenase|uridine diphospho-glucose dehydrogenase
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Interactome
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Pathway
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Disease
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