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Last updated: 2017/11/19

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UGDH rabbit monoclonal antibody

  • Catalog # : H00007358-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human UGDH peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human UGDH is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human UGDH peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7358
  • GeneBank Accession#:
  • UGDH
  • Gene Name:
  • UGDH
  • Gene Alias:
  • GDH,UDP-GlcDH,UDPGDH,UGD
  • Gene Description:
  • UDP-glucose dehydrogenase
  • Gene Summary:
  • The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq
  • Other Designations:
  • UDP-glucose 6-dehydrogenase,uridine diphospho-glucose dehydrogenase
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