UGDH purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human UGDH protein.
Immunogen
UGDH (NP_003350.1, 1 a.a. ~ 494 a.a) full-length human protein.
Sequence
MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIPKFSLQDPPNKKPKV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in human liver.Western Blot (Cell lysate)
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in MCF-7.Western Blot (Transfected lysate)
Western Blot analysis of UGDH expression in transfected 293T cell line (H00007358-T01) by UGDH MaxPab polyclonal antibody.
Lane 1: UGDH transfected lysate(54.34 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — UGDH
Entrez GeneID
7358GeneBank Accession#
NM_003359.2Protein Accession#
NP_003350.1Gene Name
UGDH
Gene Alias
GDH, UDP-GlcDH, UDPGDH, UGD
Gene Description
UDP-glucose dehydrogenase
Omim ID
603370Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. [provided by RefSeq
Other Designations
UDP-glucose 6-dehydrogenase|uridine diphospho-glucose dehydrogenase
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Interactome
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Pathway
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Disease
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