UCP2 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-UCP2 full-length
Host
Human
Theoretical MW (kDa)
33.2
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-UCP2 antibody (H00007351-B02) by Western Blots.
SDS-PAGE Gel
UCP2 transfected lysate.
Western Blot
Lane 1: UCP2 transfected lysate ( 33.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — UCP2
Entrez GeneID
7351GeneBank Accession#
NM_003355.2Protein Accession#
-Gene Name
UCP2
Gene Alias
BMIQ4, SLC25A8, UCPH
Gene Description
uncoupling protein 2 (mitochondrial, proton carrier)
Gene Ontology
HyperlinkGene Summary
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq
Other Designations
uncoupling protein 2|uncoupling protein-2
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com