UBE2V1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human UBE2V1 full-length ORF ( AAH00468, 1 a.a. - 147 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAATTGSGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTIYENRIYSLKIECGPKYPEAPPFVRFVTKINMNGVNSSNGVVDPRAISVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQCYSN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.91
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UBE2V1
Entrez GeneID
7335GeneBank Accession#
BC000468Protein Accession#
AAH00468Gene Name
UBE2V1
Gene Alias
CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
Gene Description
ubiquitin-conjugating enzyme E2 variant 1
Omim ID
602995Gene Ontology
HyperlinkGene Summary
Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq
Other Designations
DNA-binding protein|OTTHUMP00000031795|OTTHUMP00000031796|OTTHUMP00000039980
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