UBE2L3 monoclonal antibody (M01), clone 3B7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant UBE2L3.
Immunogen
UBE2L3 (AAH53368, 1 a.a. ~ 154 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
Host
Mouse
Reactivity
Human
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.68 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
UBE2L3 monoclonal antibody (M01), clone 3B7 Western Blot analysis of UBE2L3 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to UBE2L3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — UBE2L3
Entrez GeneID
7332GeneBank Accession#
BC053368Protein Accession#
AAH53368Gene Name
UBE2L3
Gene Alias
E2-F1, L-UBC, UBCH7, UbcM4
Gene Description
ubiquitin-conjugating enzyme E2L 3
Omim ID
603721Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
ubiquitin carrier protein|ubiquitin-conjugating enzyme UBCH7|ubiquitin-protein ligase
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Interactome
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Pathway
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Disease
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