UBE2D3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human UBE2D3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — UBE2D3
Entrez GeneID
7323GeneBank Accession#
NM_003340.4Protein Accession#
NP_003331.1Gene Name
UBE2D3
Gene Alias
E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Gene Description
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
Omim ID
602963Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000161758|OTTHUMP00000161759|ubiquitin carrier protein|ubiquitin-conjugating enzyme E2-17 kDa 3|ubiquitin-conjugating enzyme E2D 3|ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5)
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Interactome
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Pathway
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Disease
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