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UBE2D1 Pre-design Chimera RNAi

  • Catalog # : H00007321-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) (UBE2D1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003338
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7321
  • Gene Name:
  • UBE2D1
  • Gene Alias:
  • E2(17)KB1,SFT,UBC4/5,UBCH5,UBCH5A
  • Gene Description:
  • ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)
  • Gene Summary:
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019631,stimulator of Fe transport,ubiquitin carrier protein,ubiquitin-conjugating enzyme E2-17 kDa 1,ubiquitin-conjugating enzyme E2D 1
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