UBE2A monoclonal antibody (M01), clone 3D7-E2
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UBE2A is 0.03 ng/ml as a capture antibody.
Western Blot detection against Immunogen (42.46 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant UBE2A.
Immunogen
UBE2A (AAH10175, 1 a.a. ~ 152 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (94)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (42.46 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged UBE2A is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — UBE2A
Entrez GeneID
7319GeneBank Accession#
BC010175Protein Accession#
AAH10175Gene Name
UBE2A
Gene Alias
HHR6A, RAD6A, UBC2
Gene Description
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Omim ID
312180Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000023901|ubiquitin carrier protein A|ubiquitin-conjugating enzyme E2A|ubiquitin-protein ligase A
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Interactome
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Pathway
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