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Last updated: 2016/10/23

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UBA7 rabbit monoclonal antibody

  • Catalog # : H00007318-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human UBA7 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human UBA7 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human UBA7 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 7318
  • GeneBank Accession#:
  • UBA7
  • Gene Name:
  • UBA7
  • Gene Alias:
  • D8,MGC12713,UBA1B,UBE1L,UBE2
  • Gene Description:
  • ubiquitin-like modifier activating enzyme 7
  • Gene Summary:
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq
  • Other Designations:
  • UBA1, ubiquitin-activating enzyme E1 homolog B,UBA7, ubiquitin-activating enzyme E1,ubiquitin-activating enzyme E1-like,ubiquitin-activating enzyme E1-related protein,ubiquitin-activating enzyme-2
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