TYR (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TYR transfected lysate using rabbit polyclonal anti-TYR and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TYR.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-TYR (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-TYR (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TYR
Entrez GeneID
7299Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactome
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Pathway
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Disease
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