TYR purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human TYR protein.
Immunogen
TYR (AAH27179.1, 1 a.a. ~ 377 a.a) full-length human protein.
Sequence
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEEMGFLHVGWAGLKLLTSRDPPPWPPKMLGLQA
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in mouse kidney.Western Blot (Cell lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of TYR expression in transfected 293T cell line (H00007299-T02) by TYR MaxPab polyclonal antibody.
Lane 1: TYR transfected lysate(42.90 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TYR
Entrez GeneID
7299GeneBank Accession#
BC027179.1Protein Accession#
AAH27179.1Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactomes
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Pathways
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Diseases
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Publication Reference
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CRISPR-clear imaging of melanin-rich B16-derived solid tumors.
Rajib Schubert, Taegeun Bae, Branko Simic, Sheena N Smith, Seong-Ho Park, Gabriela Nagy-Davidescu, Viviana Gradinaru, Andreas Plückthun, Junho K Hur.
Communications Biology 2023 Apr; 6(1):370.
Application:WB-Ce, Mouse, B16 cells.
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CRISPR-clear imaging of melanin-rich B16-derived solid tumors.
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