TYR MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in mouse kidney.
Western Blot (Cell lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in HepG2.
Western Blot (Transfected lysate)
Western Blot analysis of TYR expression in transfected 293T cell line (H00007299-T02) by TYR MaxPab polyclonal antibody.
Lane 1: TYR transfected lysate(42.9 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of TYR transfected lysate using anti-TYR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TYR purified MaxPab mouse polyclonal antibody (B01P) (H00007299-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TYR protein.
Immunogen
TYR (AAH27179.1, 1 a.a. ~ 377 a.a) full-length human protein.
Sequence
MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILLSNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVRRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRDAEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEEMGFLHVGWAGLKLLTSRDPPPWPPKMLGLQA
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in mouse kidney.Western Blot (Cell lysate)
TYR MaxPab rabbit polyclonal antibody. Western Blot analysis of TYR expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of TYR expression in transfected 293T cell line (H00007299-T02) by TYR MaxPab polyclonal antibody.
Lane 1: TYR transfected lysate(42.9 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of TYR transfected lysate using anti-TYR MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TYR purified MaxPab mouse polyclonal antibody (B01P) (H00007299-B01P). -
Gene Info — TYR
Entrez GeneID
7299GeneBank Accession#
BC027179.1Protein Accession#
AAH27179.1Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactome
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Pathway
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Disease
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Publication Reference
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CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells.
Lee WR, Shen SC, Wu PR, Chou CL, Shih YH, Yeh CM, Yeh KT, Jiang MC.
Molecular Carcinogenesis 2016 Nov; 55(11):1542.
Application：WB, Mouse, B16F10 mouse melanoma cells.
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CSE1L Links cAMP/PKA and Ras/ERK pathways and regulates the expressions and phosphorylations of ERK1/2, CREB, and MITF in melanoma cells.
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