TYK2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (78); Rat (79)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TYK2 transfected lysate using mouse monoclonal anti-TYK2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TYK2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-TYK2 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-TYK2 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TYK2
Entrez GeneID
7297Gene Name
TYK2
Gene Alias
JTK1
Gene Description
tyrosine kinase 2
Omim ID
176941Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq
Other Designations
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