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TXNRD1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007296-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TXNRD1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 54.5
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TXNRD1 antibody (H00007296-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00007296-T01
    TXNRD1 transfected lysate.
    Western Blot
    QC Testing of H00007296-T01
    Lane 1: TXNRD1 transfected lysate ( 54.5 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7296
  • Protein Accession#:
  • -
  • Gene Name:
  • TXNRD1
  • Gene Alias:
  • GRIM-12,MGC9145,TR,TR1,TRXR1,TXNR
  • Gene Description:
  • thioredoxin reductase 1
  • Gene Summary:
  • This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq
  • Other Designations:
  • KM-102-derived reductase-like factor,oxidoreductase,thioredoxin reductase GRIM-12
  • Gene Pathway
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