TXNRD1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
TXNRD1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TXNRD1 expression in human kidney.
Western Blot (Cell lysate)
TXNRD1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TXNRD1 expression in HepG2.
Western Blot (Transfected lysate)
Western Blot analysis of TXNRD1 expression in transfected 293T cell line (H00007296-T02) by TXNRD1 MaxPab polyclonal antibody.
Lane 1: TXNRD1 transfected lysate(54.50 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TXNRD1 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TXNRD1 protein.
Immunogen
TXNRD1 (NP_877393.1, 1 a.a. ~ 497 a.a) full-length human protein.
Sequence
MNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGC
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TXNRD1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TXNRD1 expression in human kidney.Western Blot (Cell lysate)
TXNRD1 MaxPab rabbit polyclonal antibody. Western Blot analysis of TXNRD1 expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of TXNRD1 expression in transfected 293T cell line (H00007296-T02) by TXNRD1 MaxPab polyclonal antibody.
Lane 1: TXNRD1 transfected lysate(54.50 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to TXNRD1 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — TXNRD1
Entrez GeneID
7296GeneBank Accession#
NM_182729.1Protein Accession#
NP_877393.1Gene Name
TXNRD1
Gene Alias
GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR
Gene Description
thioredoxin reductase 1
Omim ID
601112Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq
Other Designations
KM-102-derived reductase-like factor|oxidoreductase|thioredoxin reductase GRIM-12
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Interactome
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Pathway
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Disease
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