TNFSF4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TNFSF4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TNFSF4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TNFSF4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TNFSF4
Entrez GeneID
7292GeneBank Accession#
TNFSF4Gene Name
TNFSF4
Gene Alias
CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
Gene Description
tumor necrosis factor (ligand) superfamily, member 4
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq
Other Designations
CD134 ligand|OTTHUMP00000032704|OX40 antigen ligand|OX40 ligand|glycoprotein 34 kd|tax-transcriptionally activated glycoprotein 1 (34kD)
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Pathway
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Disease
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