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Last updated: 2016/10/16

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HIRA Pre-design Chimera RNAi

  • Catalog # : H00007290-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens HIR histone cell cycle regulation defective homolog A (S. cerevisiae) (HIRA), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003325
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7290
  • Gene Name:
  • HIRA
  • Gene Alias:
  • Gene Description:
  • HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq
  • Other Designations:
  • DiGeorge critical region gene 1,HIR histone cell cycle regulation defective homolog A
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