Western blot analysis of TSTA3 over-expressed 293 cell line, cotransfected with TSTA3 Validated Chimera RNAi ( Cat # H00007264-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TSTA3 monoclonal antibody (M01), clone 2B9 (Cat # H00007264-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq
3-5 epimerase/4-reductase,GDP-4-keto-6-deoxy-D-mannose epimerase-reductase,Tissue-specific transplantation antigen-3,short chain dehydrogenase/reductase family 4E, member 1,tissue specific transplantation antigen 3