TSTA3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TSTA3 partial ORF ( NP_003304, 222 a.a. - 321 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DLAQLFIWVLREYNEVEPIILSVGEEDEVSIKEAAEAVVEAMDFHGEVTFDTTKSDGQFKKTASNSKLRTYLPDFRFTPFKQAVKETCAWFTDNYEQARK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TSTA3
Entrez GeneID
7264GeneBank Accession#
NM_003313Protein Accession#
NP_003304Gene Name
TSTA3
Gene Alias
FX, P35B, SDR4E1
Gene Description
tissue specific transplantation antigen P35B
Omim ID
137020Gene Ontology
HyperlinkGene Summary
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq
Other Designations
3-5 epimerase/4-reductase|GDP-4-keto-6-deoxy-D-mannose epimerase-reductase|Tissue-specific transplantation antigen-3|short chain dehydrogenase/reductase family 4E, member 1|tissue specific transplantation antigen 3
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Interactome
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Pathway
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