Products

Western Blot (Cell lysate)

TSTA3 monoclonal antibody (M01), clone 2B9 Western Blot analysis of TSTA3 expression in HeLa ( Cat # L013V1 ).

Western Blot (Transfected lysate)

Western Blot analysis of TSTA3 expression in transfected 293T cell line by TSTA3 monoclonal antibody (M01), clone 2B9.

Lane 1: TSTA3 transfected lysate(35.9 KDa).
Lane 2: Non-transfected lysate.

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged TSTA3 is 0.3 ng/ml as a capture antibody.

ELISA

RNAi Knockdown (Antibody validated)

Western blot analysis of TSTA3 over-expressed 293 cell line, cotransfected with TSTA3 Validated Chimera RNAi ( Cat # H00007264-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TSTA3 monoclonal antibody (M01), clone 2B9 (Cat # H00007264-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Entrez GeneID

7264

GeneBank Accession#

NM_003313

Protein Accession#

NP_003304

Gene Name

TSTA3

Gene Alias

FX, P35B, SDR4E1

Gene Description

tissue specific transplantation antigen P35B

Omim ID

137020

Gene Ontology

Hyperlink

Gene Summary

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq

Other Designations

3-5 epimerase/4-reductase|GDP-4-keto-6-deoxy-D-mannose epimerase-reductase|Tissue-specific transplantation antigen-3|short chain dehydrogenase/reductase family 4E, member 1|tissue specific transplantation antigen 3