PHLDA2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PHLDA2 partial ORF ( NP_003302, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKSPDEVLREGELEKRSDSLFQLWKKKRGVLTSDRLSLFPASPRARPKELRFHSILKVDCVERTGKYVYFTIVTTDHKEIDFRCAGESCWNAAIALALIDFQNRRALQDF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (77); Rat (75)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PHLDA2
Entrez GeneID
7262GeneBank Accession#
NM_003311Protein Accession#
NP_003302Gene Name
PHLDA2
Gene Alias
BRW1C, BWR1C, HLDA2, IPL, TSSC3
Gene Description
pleckstrin homology-like domain, family A, member 2
Omim ID
602131Gene Ontology
HyperlinkGene Summary
This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth. [provided by RefSeq
Other Designations
imprinted in placenta and liver|p17-Beckwith-Wiedemann region 1C|pleckstrin homology-like domain family A member 2|tumor suppressing subchromosomal transferable fragment cDNA 3|tumor suppressing subtransferable candidate 3|tumor-supressing STF cDNA 3
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