TSSC1 monoclonal antibody (M01), clone 2H5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TSSC1.
Immunogen
TSSC1 (NP_003301, 288 a.a. ~ 387 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL
Host
Mouse
Reactivity
Human, Rat
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TSSC1 monoclonal antibody (M01), clone 2H5 Western Blot analysis of TSSC1 expression in PC-12 ( Cat # L012V1 ).Western Blot (Transfected lysate)
Western Blot analysis of TSSC1 expression in transfected 293T cell line by TSSC1 monoclonal antibody (M01), clone 2H5.
Lane 1: TSSC1 transfected lysate (Predicted MW: 43.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TSSC1 is approximately 1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TSSC1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — TSSC1
Entrez GeneID
7260GeneBank Accession#
NM_003310Protein Accession#
NP_003301Gene Name
TSSC1
Gene Alias
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Gene Description
tumor suppressing subtransferable candidate 1
Omim ID
608998Gene Ontology
HyperlinkGene Summary
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq
Other Designations
tumor-suppressing STF cDNA 1
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